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May impair mental and/or physical abilities required for performance of hazardous tasks such as operating machinery or driving a motor vehicleconcomitant use of central nervous systemCNSdepressants or drugs associated with EPS may increase this effecte.galcoholsedativeshypnoticsopiatesand anxiolyticsavoid drug or the interacting drugdepending on importance of drug to the patient.

Galactorrheaamenorrheagynecomastiaand impotence reported with prolactin-elevating drugsincluding metoclopramidehyperprolactinemia may potentially stimulate prolactin-dependent breast cancerhoweversome clinical studies and epidemiology studies have not shown an association between administration of dopamine D2 receptor antagonists and tumorigenesis in humans.

NEVER USE METOCLOPRAMIDE IN LARGER AMOUNTS THAN RECOMMENDEDOR FOR LONGER THAN 12 WEEKSHigh doses or long-term use can cause a serious movement disorder that may not be reversibleThe longer you use metoclopramidethe more likely you are to develop this movement disorderThe risk of this side effect is higher in diabetics and older adultsespecially women

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metoclopramide may cause drowsiness, dizziness, dyskinesia and dystonias which can affect the vision and also interfere with the ability to drive and operate machinery.